Primary progressive multiple sclerosis (PPMS) is a form of the chronic disease multiple sclerosis (MS). Most people with MS start out with a clinical course characterized by episodes or attacks (relapses) of neurologic dysfunction, which occur over many years. This is called the relapsing-remitting phase. Unlike the relapsing-remitting MS, symptoms of PPMS get steadily worse, and remissions generally do not occur.
Limited approved MS and PPMS therapies are currently available. Meridian is conducting a Phase 3 clinical trial for an investigational medication for people with PPMS.
Must be age 18 to 65 and have a current diagnosis of primary progressive multiple sclerosis (PPMS)
Must have two of the following:
Documented evidence of one or more T2-hyperintense MRI lesions characteristic of MS in one or more specific brain regions
Documented evidence of two or more T2-hyperintense MRI lesions in the spinal cord
Documented evidence of the presence of cerebrospinal fluid-specific oligoclonal bands (established by a historical lumbar puncture)
Will receive compensation for study-related time
Do not need insurance to join this study
For more information, complete the form on this page. After you submit your information, a Meridian enrollment specialist will call you to talk about the study. There is no obligation to join — you can decide if the study is right for you.
You can also talk to a Meridian enrollment specialist about this study by calling (912) 623-2240.
Submit your information
Meridian Clinical Research
1520 Sunday Drive, Suite 301
Raleigh, NC 27607
After you submit your information, a Meridian enrollment specialist will contact you.
Participating in a study is an important decision — we’re here to help you before, during, and after studies.
Please note: Health insurance is NOT required to join.
Will I benefit from this study?
You are not guaranteed to benefit from being in a clinical study. However, information gathered in this study may help uncover better ways to treat condition(s) for you and others worldwide.
Is participation voluntary after I submit my information?
Yes. Participation in a study is entirely voluntary. In the informed consent process, you’ll learn about the product being studied, your role in the trial, potential side effects, tests that may be performed, and the number of visits that may be required. You will need to sign an informed consent form to join the study only after you fully understand your role in the study.
Will I get a physical exam?
If you join the study, you will receive a physical exam. You may also receive specific exams or tests — the results of which may be shared with you.
Will I receive compensation?
While participation in a clinical study is voluntary, you may be reimbursed for study-related time and expenses. After you submit your information, a Meridian enrollment specialist will call you to talk about the study. Staff at the research clinic will discuss possible reimbursement with you.
Founded in 1999 in Omaha, NE, Meridian studies the safety and effectiveness of new medicines, devices, and treatments. Its mission is to enrich lives by providing quality, compassionate care to patients and unparalleled clinical research services. Clinical studies help scientists develop life-changing medicines, but it starts with you — participation makes it all possible. For more than 20 years, thousands of patients have trusted Meridian because of our focus on creating a positive patient experience.