Monkeypox and Smallpox Vaccine and Medication Study

Now Enrolling

  • Ages: 18-42
  • Location: Omaha, NE
  • Compensation: Up to $2,500

In this study, participants will receive an FDA-approved vaccine (JYNNEOS) for prevention of smallpox and monkeypox at no cost, and an FDA-approved oral antiviral medication (TPOXX) or placebo. The main objective of this study is to learn whether or not your body will make a protective substance called an antibody after receiving the JYNNEOS vaccine together with TPOXX. No participants will be exposed to smallpox or monkeypox as part of this study.

Eligible participants…

  • Must be a healthy adult between the ages of 18 and 42
  • Must weigh less than 265 lbs. (120 kgs)
  • Will receive up to $2,500 in compensation for study-related time
  • Will receive an FDA-approved vaccine for prevention of smallpox and monkeypox at no cost
  • Do not need insurance to join this study

For more information, complete the form on this page. After you submit your information, a Meridian enrollment specialist will call you to talk about the study. There is no obligation to join — you can decide if the study is right for you.

You can also talk to a Meridian enrollment specialist about this study by calling (402) 934-7563.

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Study Location

Meridian Clinical Research
3319 N 107th St
Omaha, NE 68134

Founded in 1999 in Omaha, NE, Meridian studies the safety and effectiveness of new medicines, devices, and treatments. Its mission is to enrich lives by providing quality, compassionate care to patients and unparalleled clinical research services. Clinical studies help scientists develop life-changing medicines, but it starts with you — participation makes it all possible. For more than 20 years, thousands of patients have trusted Meridian because of our focus on creating a positive patient experience.