In this study, participants will receive an FDA-approved vaccine (JYNNEOS) for prevention of smallpox and monkeypox at no cost, and an FDA-approved oral antiviral medication (TPOXX) or placebo. The main objective of this study is to learn whether or not your body will make a protective substance called an antibody after receiving the JYNNEOS vaccine together with TPOXX. No participants will be exposed to smallpox or monkeypox as part of this study.
Must be a healthy adult between the ages of 18 and 42
Must weigh less than 265 lbs. (120 kgs)
Will receive up to $2,500 in compensation for study-related time
Will receive an FDA-approved vaccine for prevention of smallpox and monkeypox at no cost
Do not need insurance to join this study
For more information, complete the form on this page. After you submit your information, a Meridian enrollment specialist will call you to talk about the study. There is no obligation to join — you can decide if the study is right for you.
You can also talk to a Meridian enrollment specialist about this study by calling (402) 934-7563.
Submit your information
Meridian Clinical Research
3319 N 107th St
Omaha, NE 68134
After you submit your information, a Meridian enrollment specialist will contact you.
Participating in a study is an important decision — we’re here to help you before, during, and after studies.
Please note: Health insurance is NOT required to join.
Will I benefit from this study?
You are not guaranteed to benefit from being in a clinical study. However, information gathered in this study may help uncover better ways to treat condition(s) for you and others worldwide.
Is participation voluntary after I submit my information?
Yes. Participation in a study is entirely voluntary. In the informed consent process, you’ll learn about the product being studied, your role in the trial, potential side effects, tests that will be performed, and the number of visits required. You will need to sign an informed consent form to join the study only after you fully understand your role in the study.
Will I get a physical exam?
If you join the study, you will receive a physical exam. You may also receive specific exams or tests — the results of which will be shared with you.
Will I receive compensation?
While participation in a clinical study is voluntary, you may be reimbursed for study-related time. After you submit your information, a Meridian enrollment specialist will call you to talk about the study. Staff at the research clinic will discuss possible reimbursement with you.
Founded in 1999 in Omaha, NE, Meridian studies the safety and effectiveness of new medicines, devices, and treatments. Its mission is to enrich lives by providing quality, compassionate care to patients and unparalleled clinical research services. Clinical studies help scientists develop life-changing medicines, but it starts with you — participation makes it all possible. For more than 20 years, thousands of patients have trusted Meridian because of our focus on creating a positive patient experience.