Variola virus infection causes smallpox, which is a highly contagious and often deadly disease that has plagued humans throughout history. Naturally occurring smallpox was eradicated by the early 1980s due to vaccination, and most Americans no longer received a smallpox vaccine after the early 1970s.
In this study, participants will receive an FDA-approved oral antiviral medication intended for the treatment of smallpox, or placebo. The goal of this study is to assess the tolerability of the medication when taken for a longer period than what is currently approved by the FDA.
No participants will be exposed to smallpox as part of this study — blood draws are taken to assess the medication’s effect.
Must be a healthy adult between the ages of 18 and 80
Will receive compensation for study-related time
Do not need insurance to join this study
For more information, complete the form on this page. After you submit your information, a Meridian enrollment specialist will call you to talk about the study. There is no obligation to join — you can decide if the study is right for you.
You can also talk to a Meridian enrollment specialist about this study by calling (402) 934-7563.
Submit your information
Meridian Clinical Research
3319 N 107th St
Omaha, NE 68134
After you submit your information, a Meridian enrollment specialist will contact you.
Participating in a study is an important decision — we’re here to help you before, during, and after studies.
Please note: Health insurance is NOT required to join.
Will I benefit from this study?
You are not guaranteed to benefit from being in a clinical study. However, information gathered in this study may help uncover better ways to treat condition(s) for you and others worldwide.
Is participation voluntary after I submit my information?
Yes. Participation in a study is entirely voluntary. In the informed consent process, you’ll learn about the product being studied, your role in the trial, potential side effects, tests that will be performed, and the number of visits required. You will need to sign an informed consent form to join the study only after you fully understand your role in the study.
Will I get a physical exam?
If you join the study, you will receive a physical exam. You may also receive specific exams or tests — the results of which will be shared with you.
Will I receive compensation?
While participation in a clinical study is voluntary, you may be reimbursed for study-related time. After you submit your information, a Meridian enrollment specialist will call you to talk about the study. Staff at the research clinic will discuss possible reimbursement with you.
Founded in 1999 in Omaha, NE, Meridian studies the safety and effectiveness of new medicines, devices, and treatments. Its mission is to enrich lives by providing quality, compassionate care to patients and unparalleled clinical research services. Clinical studies help scientists develop life-changing medicines, but it starts with you — participation makes it all possible. For more than 20 years, thousands of patients have trusted Meridian because of our focus on creating a positive patient experience.